Skeleton-Based Structural Optimization

Skeleton-Based Structural Optimization


Latest company news about Skeleton-Based Structural Optimization

KS-V Peptide has an expert team of structural biologists with strong academic and industrial experience and can offer high-quality structural biology services to pharmaceuticals, biotechnology companies, and research institutions. Our team's expertise and state-of-the-art technology allow us to provide unparalleled services that meet the needs of our clients.


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        For the purpose of improving the exceptional quality and reliability of our peptide products, we have been contentiously developing specific skills and expertise for making difficult-to-synthesize peptides in excellent quality for a long-term. The specific products include modified peptide, monocyclic, bicyclic, and polycyclic peptide, stapled peptide, D-type peptide, and etc. We also provide unnatural amino acid substitution and Peptide drug coupling technology.

        These products and services improve metabolic stability of peptide structures, make peptide form secondary structures in solution, increase affinity, reduce the risk of off-target effect or being hydrolyzed by protease.


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  • The current challenges in peptide drug development include poor stability, short half-life, high plasma clearance rate, and other suboptimal pharmaceutical properties, as well as limited oral availability and poor patient compliance.
  • To address these issues, KS-V Peptide provides a variety of peptide modification services to improve the druggability of the peptides while reduce the production cost.
  • Our strategies include peptide backbone modifications and peptide side chain modifications, such as using unnatural amino acids, pseudopeptides, cyclized peptides, conjugation with fatty acids, polyethylene glycol, etc..


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