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Peptide Modification

Peptide modifications refer to the chemical or enzymatic alterations performed on a peptide's amino acid sequence, to achieve various functional improvements, including increased solubility, enhanced stability, improved pharmacokinetics, enhanced selectivity and specificity, and many more. KS-V Peptide offers hundreds of peptide modifications to meet your research need. Our team of highly skilled scientists will choose the most suitable methods and techniques tailored to each project.

 

  • N-terminal modifications (an incomplete list, other modifications available upon request)

 

3-Mercaptopropyl (MPA) D (+) Glucose Lauric acid
5-FAM Dansyl Lipoic acid
5-FAM-Ahx Dansyl-Ahx Maleimide
Abz Decanoic acid 7-Methoxycoumarinyl-4-acetyl (MCA)
Acetylation 2, 4-Dinitrophenyl (DNP) Myristoyl
Acryl DTPA Octanoic acid
Alloc Fatty Acid OVA (-NH2 of N terminal)
Benzoyl FITC Palmytoyl
Benzyloxycarbonylation (CBZ) FITC-Ahx Pentinoic Acid
Biotin Fmoc Propiolic Acid
Biotin-Ahx Formylation Pyroglutamyl (pGlu) (Pyr)
Tertbutoxycarbonyl (Boc) Hexanoic acid Stearic acid
Br-Ac- HYNIC Succinylation
BSA (-NH2 of N terminal) 4-Hydroxyphenylpropionic acid (HPP) Thioester
Chenodeoxycholic acid KLH (-NH2 of N terminal) TMR

 

 

  • C-terminal modifications (an incomplete list, other modifications available upon request)

 

 

AFC OtBu Me
AMC OBzl NHEt
Amidation EDA-Biotin NHisopen
BSA (-COOH of C terminal) Ethylamine NHMe/NHEt
Bzl Fuoro-methylketones (FMK) OSU
Chloro-methylketones (CMK) Hydrazine OVA (-COOH of C terminal)
C-terminaleaters KLH (-COOH of C terminal) p-Nitroanilide (PNA)
Cysteamide MAPS Asymmetric 2 branches tBu
OMe MAPS Asymmetric 4 branches TBzl
OEt MAPS Asymmetric 8 branches Thioester

 

 

Other modifications

 

  • Stable isotope labeled peptides.
  • Fluorescent peptide modifications/FRET pairs
  • Peptide conjugates.
  • Other modifications are available upon request.
Products
PEPTIDE DISCOVERY
Home >

lead optimization >

Peptide Modification

Peptide modifications refer to the chemical or enzymatic alterations performed on a peptide's amino acid sequence, to achieve various functional improvements, including increased solubility, enhanced stability, improved pharmacokinetics, enhanced selectivity and specificity, and many more. KS-V Peptide offers hundreds of peptide modifications to meet your research need. Our team of highly skilled scientists will choose the most suitable methods and techniques tailored to each project.

 

  • N-terminal modifications (an incomplete list, other modifications available upon request)

 

3-Mercaptopropyl (MPA) D (+) Glucose Lauric acid
5-FAM Dansyl Lipoic acid
5-FAM-Ahx Dansyl-Ahx Maleimide
Abz Decanoic acid 7-Methoxycoumarinyl-4-acetyl (MCA)
Acetylation 2, 4-Dinitrophenyl (DNP) Myristoyl
Acryl DTPA Octanoic acid
Alloc Fatty Acid OVA (-NH2 of N terminal)
Benzoyl FITC Palmytoyl
Benzyloxycarbonylation (CBZ) FITC-Ahx Pentinoic Acid
Biotin Fmoc Propiolic Acid
Biotin-Ahx Formylation Pyroglutamyl (pGlu) (Pyr)
Tertbutoxycarbonyl (Boc) Hexanoic acid Stearic acid
Br-Ac- HYNIC Succinylation
BSA (-NH2 of N terminal) 4-Hydroxyphenylpropionic acid (HPP) Thioester
Chenodeoxycholic acid KLH (-NH2 of N terminal) TMR

 

 

  • C-terminal modifications (an incomplete list, other modifications available upon request)

 

 

AFC OtBu Me
AMC OBzl NHEt
Amidation EDA-Biotin NHisopen
BSA (-COOH of C terminal) Ethylamine NHMe/NHEt
Bzl Fuoro-methylketones (FMK) OSU
Chloro-methylketones (CMK) Hydrazine OVA (-COOH of C terminal)
C-terminaleaters KLH (-COOH of C terminal) p-Nitroanilide (PNA)
Cysteamide MAPS Asymmetric 2 branches tBu
OMe MAPS Asymmetric 4 branches TBzl
OEt MAPS Asymmetric 8 branches Thioester

 

 

Other modifications

 

  • Stable isotope labeled peptides.
  • Fluorescent peptide modifications/FRET pairs
  • Peptide conjugates.
  • Other modifications are available upon request.