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    Peptide Modification

    Peptide modifications refer to the chemical or enzymatic alterations performed on a peptide's amino acid sequence, to achieve various functional improvements, including increased solubility, enhanced stability, improved pharmacokinetics, enhanced selectivity and specificity, and many more. KS-V Peptide offers hundreds of peptide modifications to meet your research need. Our team of highly skilled scientists will choose the most suitable methods and techniques tailored to each project.

     

    • N-terminal modifications (an incomplete list, other modifications available upon request)

     

    3-Mercaptopropyl (MPA) D (+) Glucose Lauric acid
    5-FAM Dansyl Lipoic acid
    5-FAM-Ahx Dansyl-Ahx Maleimide
    Abz Decanoic acid 7-Methoxycoumarinyl-4-acetyl (MCA)
    Acetylation 2, 4-Dinitrophenyl (DNP) Myristoyl
    Acryl DTPA Octanoic acid
    Alloc Fatty Acid OVA (-NH2 of N terminal)
    Benzoyl FITC Palmytoyl
    Benzyloxycarbonylation (CBZ) FITC-Ahx Pentinoic Acid
    Biotin Fmoc Propiolic Acid
    Biotin-Ahx Formylation Pyroglutamyl (pGlu) (Pyr)
    Tertbutoxycarbonyl (Boc) Hexanoic acid Stearic acid
    Br-Ac- HYNIC Succinylation
    BSA (-NH2 of N terminal) 4-Hydroxyphenylpropionic acid (HPP) Thioester
    Chenodeoxycholic acid KLH (-NH2 of N terminal) TMR

     

     

    • C-terminal modifications (an incomplete list, other modifications available upon request)

     

     

    AFC OtBu Me
    AMC OBzl NHEt
    Amidation EDA-Biotin NHisopen
    BSA (-COOH of C terminal) Ethylamine NHMe/NHEt
    Bzl Fuoro-methylketones (FMK) OSU
    Chloro-methylketones (CMK) Hydrazine OVA (-COOH of C terminal)
    C-terminaleaters KLH (-COOH of C terminal) p-Nitroanilide (PNA)
    Cysteamide MAPS Asymmetric 2 branches tBu
    OMe MAPS Asymmetric 4 branches TBzl
    OEt MAPS Asymmetric 8 branches Thioester

     

     

    Other modifications

     

    • Stable isotope labeled peptides.
    • Fluorescent peptide modifications/FRET pairs
    • Peptide conjugates.
    • Other modifications are available upon request.
    Products
    PEPTIDE DISCOVERY
    Home >

    lead optimization >

    Peptide Modification

    Peptide modifications refer to the chemical or enzymatic alterations performed on a peptide's amino acid sequence, to achieve various functional improvements, including increased solubility, enhanced stability, improved pharmacokinetics, enhanced selectivity and specificity, and many more. KS-V Peptide offers hundreds of peptide modifications to meet your research need. Our team of highly skilled scientists will choose the most suitable methods and techniques tailored to each project.

     

    • N-terminal modifications (an incomplete list, other modifications available upon request)

     

    3-Mercaptopropyl (MPA) D (+) Glucose Lauric acid
    5-FAM Dansyl Lipoic acid
    5-FAM-Ahx Dansyl-Ahx Maleimide
    Abz Decanoic acid 7-Methoxycoumarinyl-4-acetyl (MCA)
    Acetylation 2, 4-Dinitrophenyl (DNP) Myristoyl
    Acryl DTPA Octanoic acid
    Alloc Fatty Acid OVA (-NH2 of N terminal)
    Benzoyl FITC Palmytoyl
    Benzyloxycarbonylation (CBZ) FITC-Ahx Pentinoic Acid
    Biotin Fmoc Propiolic Acid
    Biotin-Ahx Formylation Pyroglutamyl (pGlu) (Pyr)
    Tertbutoxycarbonyl (Boc) Hexanoic acid Stearic acid
    Br-Ac- HYNIC Succinylation
    BSA (-NH2 of N terminal) 4-Hydroxyphenylpropionic acid (HPP) Thioester
    Chenodeoxycholic acid KLH (-NH2 of N terminal) TMR

     

     

    • C-terminal modifications (an incomplete list, other modifications available upon request)

     

     

    AFC OtBu Me
    AMC OBzl NHEt
    Amidation EDA-Biotin NHisopen
    BSA (-COOH of C terminal) Ethylamine NHMe/NHEt
    Bzl Fuoro-methylketones (FMK) OSU
    Chloro-methylketones (CMK) Hydrazine OVA (-COOH of C terminal)
    C-terminaleaters KLH (-COOH of C terminal) p-Nitroanilide (PNA)
    Cysteamide MAPS Asymmetric 2 branches tBu
    OMe MAPS Asymmetric 4 branches TBzl
    OEt MAPS Asymmetric 8 branches Thioester

     

     

    Other modifications

     

    • Stable isotope labeled peptides.
    • Fluorescent peptide modifications/FRET pairs
    • Peptide conjugates.
    • Other modifications are available upon request.