Alpha-2 Plasmin Inhibitor; Serpin Peptidase Inhibitor,Catalog Number: KS051007,Molecular Weight:800.82
The primary physiological inhibitor of plasmin is a2–plasmin inhibitor. The binding of a2 –plasmin inhibitor to plasmin(ogen) plays a critical role in fibrinolysis. The binding of circulating free plasmin(ogen) by a2 –plasmin inhibitor prevents both zymogen and enzyme from binding to fibrin and ultimately initiating fibrinolysis. a2–Plasmin inhibitor already crosslinked to fibrin prevents plasmin catalytic action on local sites of fibrin deposition as well as impeding subsequent activation of plasminogen via plasminogen activator.
Alpha-2 Plasmin Inhibitor; Serpin Peptidase Inhibitor,Catalog Number: KS051007,Molecular Weight:800.82
The primary physiological inhibitor of plasmin is a2–plasmin inhibitor. The binding of a2 –plasmin inhibitor to plasmin(ogen) plays a critical role in fibrinolysis. The binding of circulating free plasmin(ogen) by a2 –plasmin inhibitor prevents both zymogen and enzyme from binding to fibrin and ultimately initiating fibrinolysis. a2–Plasmin inhibitor already crosslinked to fibrin prevents plasmin catalytic action on local sites of fibrin deposition as well as impeding subsequent activation of plasminogen via plasminogen activator.