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Lyophilized scorpion Kurtoxin CAS 820959-57-7 Catalog Number C1090-V

Lyophilized scorpion Kurtoxin CAS 820959-57-7 Catalog Number C1090-V

Product Details:
Catalog Number:
C1090-V
Product Name:
Kurtoxin
Scale:
50 μg
Price:
$611
Purity:
≥95%
Channel Type:
Ca2+ Channel Blocker
Sequence:
KIDGYPVDYWNCKRICWYNNKYCNDLCKGLKADSGYCWGWTLSCYCQGLPDNARIKRSGRCRA
Molecular Formula:
C324 H478 N94O90S8
Molecular Weight:
7386.36
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
High Light: 

Lyophilized kurtoxin

,

Scorpion kurtoxin

,

CAS 820959-57-7

Product Description

kurtoxin,CAS#:820959-57-7,Lyophilized,Catalog Number: C1090-V

 

Kurtoxin is a compound found in scorpion toxin, and is a T-type Ca2+ channel blocker.

Chemistry

Kurtoxin is a protein containing 63 amino acid residues with a mass of 7386.1 daltons. Its formula is C324H478N94O90S8. It can be isolated from the venom of Parabuthus transvaalicus by high-performance liquid chromatography (HPLC). Kurtoxin is closely related to α-scorpion toxins, a family of toxins that slow inactivation of voltage-gated sodium channels. The complete primary amino-acid sequence of kurtoxin is: KIDGYPVDYW NCKRICWYNN KYCNDLCKGL KADSGYCWGW TLSCYCQGLP DNARIKRSGR CRA.

Target

In research on Xenopus oocytes it was found that kurtoxin affects low-threshold α1G and α1H calcium channels, but not the high-threshold α1A, α1B, α1C, and α1E Ca channels. Like other α-scorpion toxins kurtoxin was also found to interact with voltage-gated sodium channels. In rat neurons, less selectivity for kurtoxin on calcium channels is found. Here the toxin interacts with high affinity with T-type, L-type, N-type, and P-type channels.

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products details
Home > Products >
Lyophilized scorpion Kurtoxin CAS 820959-57-7 Catalog Number C1090-V

Lyophilized scorpion Kurtoxin CAS 820959-57-7 Catalog Number C1090-V

Product Details:
Catalog Number:
C1090-V
Product Name:
Kurtoxin
Scale:
50 μg
Price:
$611
Purity:
≥95%
Channel Type:
Ca2+ Channel Blocker
Sequence:
KIDGYPVDYWNCKRICWYNNKYCNDLCKGLKADSGYCWGWTLSCYCQGLPDNARIKRSGRCRA
Molecular Formula:
C324 H478 N94O90S8
Molecular Weight:
7386.36
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
Details Link:
Https://shopping.ks-vpeptide.com/sale-470710-lyophilized-scorpion-kurtoxin-cas-820959-57-7-catalog-number-c1090-v.htm
High Light: 

Lyophilized kurtoxin

,

Scorpion kurtoxin

,

CAS 820959-57-7

Product Description

kurtoxin,CAS#:820959-57-7,Lyophilized,Catalog Number: C1090-V

 

Kurtoxin is a compound found in scorpion toxin, and is a T-type Ca2+ channel blocker.

Chemistry

Kurtoxin is a protein containing 63 amino acid residues with a mass of 7386.1 daltons. Its formula is C324H478N94O90S8. It can be isolated from the venom of Parabuthus transvaalicus by high-performance liquid chromatography (HPLC). Kurtoxin is closely related to α-scorpion toxins, a family of toxins that slow inactivation of voltage-gated sodium channels. The complete primary amino-acid sequence of kurtoxin is: KIDGYPVDYW NCKRICWYNN KYCNDLCKGL KADSGYCWGW TLSCYCQGLP DNARIKRSGR CRA.

Target

In research on Xenopus oocytes it was found that kurtoxin affects low-threshold α1G and α1H calcium channels, but not the high-threshold α1A, α1B, α1C, and α1E Ca channels. Like other α-scorpion toxins kurtoxin was also found to interact with voltage-gated sodium channels. In rat neurons, less selectivity for kurtoxin on calcium channels is found. Here the toxin interacts with high affinity with T-type, L-type, N-type, and P-type channels.