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ShK Toxin Peptide Toxins CAS 172450-46-3 Catalog Number K1010-V

ShK Toxin Peptide Toxins CAS 172450-46-3 Catalog Number K1010-V

Product Details:
Catalog Number:
K1010-V
Product Name:
ShK Toxin
Scale:
50 μg
Price:
$96
Purity:
≥95%
Channel Type:
K+ Channel Blocker
Sequence:
RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
Molecular Formula:
C169 H274 N54O48S7
Molecular Weight:
4055 Da
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
High Light: 

ShK Peptide Toxins

,

Peptide Toxins 172450-46-3

,

ShK Toxin 172450-46-3

Product Description

ShK Toxin,CAS#:172450-46-3,Catalog Number: K1010-V,Sequence:RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC

 

Various KV K+ channels. Stichodactyla Toxin blocks KV1.3, KV1.1, KV1.4, and KV1.6 at subnanomolar concentrations and KV3.2 channels at 1000-fold higher concentration than that required to inhibit KV1.3 channels.

Structure

ShK is cross-linked by three disulfide bridges: Cys3-Cys35, Cys12-Cys28, and Cys17-Cys32. The solution structure of ShK reveals two short α-helices comprising residues 14-19 and 21–24; the N-terminal eight residues adopt an extended conformation, followed by a pair of interlocking turns that resemble a 310 helix; the C-terminal Cys35 residue forms a nearly head-to-tail cyclic structure through a disulfide bond with Cys3.

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products details
Home > Products >
ShK Toxin Peptide Toxins CAS 172450-46-3 Catalog Number K1010-V

ShK Toxin Peptide Toxins CAS 172450-46-3 Catalog Number K1010-V

Product Details:
Catalog Number:
K1010-V
Product Name:
ShK Toxin
Scale:
50 μg
Price:
$96
Purity:
≥95%
Channel Type:
K+ Channel Blocker
Sequence:
RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
Molecular Formula:
C169 H274 N54O48S7
Molecular Weight:
4055 Da
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
Details Link:
Https://shopping.ks-vpeptide.com/sale-470910-shk-toxin-peptide-toxins-cas-172450-46-3-catalog-number-k1010-v.htm
High Light: 

ShK Peptide Toxins

,

Peptide Toxins 172450-46-3

,

ShK Toxin 172450-46-3

Product Description

ShK Toxin,CAS#:172450-46-3,Catalog Number: K1010-V,Sequence:RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC

 

Various KV K+ channels. Stichodactyla Toxin blocks KV1.3, KV1.1, KV1.4, and KV1.6 at subnanomolar concentrations and KV3.2 channels at 1000-fold higher concentration than that required to inhibit KV1.3 channels.

Structure

ShK is cross-linked by three disulfide bridges: Cys3-Cys35, Cys12-Cys28, and Cys17-Cys32. The solution structure of ShK reveals two short α-helices comprising residues 14-19 and 21–24; the N-terminal eight residues adopt an extended conformation, followed by a pair of interlocking turns that resemble a 310 helix; the C-terminal Cys35 residue forms a nearly head-to-tail cyclic structure through a disulfide bond with Cys3.