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Margatoxin Peptide CAS 145808-47-5 Catalog Number K1020-V

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Margatoxin Peptide CAS 145808-47-5 Catalog Number K1020-V

Product Details:

Catalog Number:

K1020-V

Product Name:

Margatoxin

Scale:

50 μg

Price:

$161

Purity:

≥95%

Channel Type:

K⁺Channel Blocker

Sequence:

TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH

Molecular Formula:

C₁₇₈ H₂₈₆ N₅₂O₅₀S₇

Molecular Weight:

4179.03 Da

Form:

Lyophilized

Storage:

Store At -20°C Or -80°C

High Light:

Margatoxin K1020-V

Margatoxin 145808-47-5

CAS 145808-47-5

Product Description

Margatoxin,CAS#:145808-47-5,Catalog Number:K1020-V,Store at -20°C or -80°C

Kv1.3 selective blocker

Margatoxin (MgTX) is a peptide that selectively inhibits Kv1.3 voltage-dependent potassium channels. It is found in the venom of Centruroides margaritatus, also known as the Central American Bark Scorpion. Margatoxin was first discovered in 1993. It was purified from scorpion venom and its amino acid sequence was determined.

Structure

Margatoxin is a peptide of 39 amino acids with a molecular weight of 4185 Dalton. The primary amino acid sequence of margatoxin is as follows:

Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His

Or, when translated to one-letter sequence,

TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH.

There are disulfide bridges between Cys7-Cys29, Cys13-Cys34 and Cys17-Cys36.

Margatoxin is classified as a "scorpion short toxin" by Pfam, showing sequence homology with other potassium channel blockers, such as charybdotoxin (44%), kaliotoxin (54%), iberiotoxin (41%) and noxiustoxin (79%), which are also derived from scorpion venom.

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Margatoxin K1020-V,

Margatoxin 145808-47-5,

CAS 145808-47-5

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Margatoxin Peptide CAS 145808-47-5 Catalog Number K1020-V

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Margatoxin Peptide CAS 145808-47-5 Catalog Number K1020-V

Product Details:

Catalog Number:

K1020-V

Product Name:

Margatoxin

Scale:

50 μg

Price:

$161

Purity:

≥95%

Channel Type:

K⁺Channel Blocker

Sequence:

TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH

Molecular Formula:

C₁₇₈ H₂₈₆ N₅₂O₅₀S₇

Molecular Weight:

4179.03 Da

Form:

Lyophilized

Storage:

Store At -20°C Or -80°C

Details Link:

Https://shopping.ks-vpeptide.com/sale-470935-margatoxin-peptide-cas-145808-47-5-catalog-number-k1020-v.htm

High Light:

Margatoxin K1020-V

Margatoxin 145808-47-5

CAS 145808-47-5

Product Description

Margatoxin,CAS#:145808-47-5,Catalog Number:K1020-V,Store at -20°C or -80°C

Kv1.3 selective blocker

Structure

Margatoxin is a peptide of 39 amino acids with a molecular weight of 4185 Dalton. The primary amino acid sequence of margatoxin is as follows:

Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His

Or, when translated to one-letter sequence,

TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH.

There are disulfide bridges between Cys7-Cys29, Cys13-Cys34 and Cys17-Cys36.

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