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H2A-K15Ub,Lyophilized,Catalog Number: H1402,Store at -20°C or -80°C

H2A-K15Ub,Lyophilized,Catalog Number: H1402,Store at -20°C or -80°C

Product Details:
Catalog Number:
H1402
Product Name:
H2A-K15Ub
Scale:
50 μg
Purity:
≥95%
Price:
$885
CAS#.:
N/A
Sequence:
SGRGKQGGKA RAKAKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKAKGK
Molecular Formula:
C994H1671N303O288S1
Molecular Weight:
22507.12
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
Product Description

H2A-K15Ub Catalog Number H1402 Store at -20°C or -80°C

 

Chemically synthesized histone H2A protein (1-129,human) with mono-ubiquitination at K15. Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. RNF168-mediated ubiquitination of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining genome stability. USP51 is the DUB for H2AK13,15ub and regulates DNA damage response.

 

53BP1 recruitment to DSBs is triggered by RNF168-mediated ubiquitylation of histone H2A lysine 15 in the nucleosome core particle (NCP) constitutively dimethylated at histone H4 lysine 20 (NCPH2AK15ubH4K20me2), modifications recognized by 53BP1.

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products details
Home > Products >
H2A-K15Ub,Lyophilized,Catalog Number: H1402,Store at -20°C or -80°C

H2A-K15Ub,Lyophilized,Catalog Number: H1402,Store at -20°C or -80°C

Product Details:
Catalog Number:
H1402
Product Name:
H2A-K15Ub
Scale:
50 μg
Purity:
≥95%
Price:
$885
CAS#.:
N/A
Sequence:
SGRGKQGGKA RAKAKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKAKGK
Molecular Formula:
C994H1671N303O288S1
Molecular Weight:
22507.12
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
Details Link:
Https://shopping.ks-vpeptide.com/sale-470575-h2a-k15ub-lyophilized-catalog-number-h1402-store-at-20-c-or-80-c.htm
Product Description

H2A-K15Ub Catalog Number H1402 Store at -20°C or -80°C

 

Chemically synthesized histone H2A protein (1-129,human) with mono-ubiquitination at K15. Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. RNF168-mediated ubiquitination of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining genome stability. USP51 is the DUB for H2AK13,15ub and regulates DNA damage response.

 

53BP1 recruitment to DSBs is triggered by RNF168-mediated ubiquitylation of histone H2A lysine 15 in the nucleosome core particle (NCP) constitutively dimethylated at histone H4 lysine 20 (NCPH2AK15ubH4K20me2), modifications recognized by 53BP1.