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H2B-S14ph Catalog Number H2301 Store at -20°C or -80°C
Chemically synthesized histone H2B protein corresponding to residues within 1-125 of human histone H2B with phosphorylation S14 modification.
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. Phosphorylation of histone H2B at serine 14 (H2B-S14Ph) is associated with DNA damage and induces apoptotic chromatin condensation. H2B-S14Ph also correlates with class switch recombination and somatic hypermutation in germinal center B cells.
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H2B-S14ph Catalog Number H2301 Store at -20°C or -80°C
Chemically synthesized histone H2B protein corresponding to residues within 1-125 of human histone H2B with phosphorylation S14 modification.
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. Phosphorylation of histone H2B at serine 14 (H2B-S14Ph) is associated with DNA damage and induces apoptotic chromatin condensation. H2B-S14Ph also correlates with class switch recombination and somatic hypermutation in germinal center B cells.