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H3K4me3 Catalog Number H3103 Lyophilized Store At -20°C Or -80°C
Chemically synthesized histone H3 protein, corresponding to residues within 1-135 of human histone H3, trimethylation at K4.
H3K4me3 is commonly associated with the activation of transcription of nearby genes. H3K4 trimethylation regulates gene expression through chromatin remodeling by the NURF complex. This makes the DNA in the chromatin more accessible for transcription factors, allowing the genes to be transcribed and expressed in the cell.
More specifically, H3K4me3 is found to positively regulate transcription by bringing histone acetylases and nucleosome remodeling enzymes (NURF). H3K4me3 also plays an important role in the genetic regulation of stem cell potency and lineage. This is because this histone modification is more-so found in areas of the DNA that are associated with development and establishing cell identity.
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H3K4me3 Catalog Number H3103 Lyophilized Store At -20°C Or -80°C
Chemically synthesized histone H3 protein, corresponding to residues within 1-135 of human histone H3, trimethylation at K4.
H3K4me3 is commonly associated with the activation of transcription of nearby genes. H3K4 trimethylation regulates gene expression through chromatin remodeling by the NURF complex. This makes the DNA in the chromatin more accessible for transcription factors, allowing the genes to be transcribed and expressed in the cell.
More specifically, H3K4me3 is found to positively regulate transcription by bringing histone acetylases and nucleosome remodeling enzymes (NURF). H3K4me3 also plays an important role in the genetic regulation of stem cell potency and lineage. This is because this histone modification is more-so found in areas of the DNA that are associated with development and establishing cell identity.