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ASIC1a Channels Psalmotoxin 1 Catalog Number O1120-V

ASIC1a Channels Psalmotoxin 1 Catalog Number O1120-V

Product Details:
Catalog Number:
O1120-V
Product Name:
Psalmotoxin 1
Scale:
50 μg
Price:
$161
Purity:
≥95%
Channel Type:
Other Blockers
Sequence:
EDCIPKWKGCVNRHGDCCEGLECWKRRRSFEVCVPKTPKT
Molecular N/AFormula:
C200H312N62O57S6
Molecular Weight:
4689.5 Da
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
High Light: 

ASIC1a psalmotoxin 1

,

O1120-V psalmotoxin 1

,

ASIC1a Psalmotoxin

Product Description

Psalmotoxin 1,Catalog Number: O1120-V,Lyophilized,Purity≥95%

 

ASIC1a channels, Psalmotoxin-1 inhibits cation currents mediated by acid-sensing ion channels (ASIC1a).

Psalmotoxin (PcTx1) is a spider toxin from the venom of the Trinidad tarantula Psalmopoeus cambridgei. It selectively blocks Acid Sensing Ion Channel 1-a (ASIC1a), which is a proton-gated sodium channel.

Sources


Psalmotoxin is a toxin produced in the venom glands of the South American tarantula Psalmopoeus cambridgei.

Chemistry


The psalmotoxin structure can be classified as an inhibitor cystine knot (ICK) protein. Many ion channel effectors from snail, spider, and scorpion venoms share a similar ICK structure, although they possess very different pharmalogical profiles. Among ICK toxins, psalmotoxin is the only peptide known to act on homomeric ASIC1 channels.

Psalmotoxin is a 40-amino acid peptide, possessing 6 cysteines linked by three disulfide bridges. The three-dimensional structure consists of a compact disulfide-bonded core from which three loops and the N and C termini emerge. The main element of the structure is a three-stranded antiparallel β-sheet.

Products
products details
Home > Products >
ASIC1a Channels Psalmotoxin 1 Catalog Number O1120-V

ASIC1a Channels Psalmotoxin 1 Catalog Number O1120-V

Product Details:
Catalog Number:
O1120-V
Product Name:
Psalmotoxin 1
Scale:
50 μg
Price:
$161
Purity:
≥95%
Channel Type:
Other Blockers
Sequence:
EDCIPKWKGCVNRHGDCCEGLECWKRRRSFEVCVPKTPKT
Molecular N/AFormula:
C200H312N62O57S6
Molecular Weight:
4689.5 Da
Form:
Lyophilized
Storage:
Store At -20°C Or -80°C
Details Link:
Https://shopping.ks-vpeptide.com/sale-470932-asic1a-channels-psalmotoxin-1-catalog-number-o1120-v.htm
High Light: 

ASIC1a psalmotoxin 1

,

O1120-V psalmotoxin 1

,

ASIC1a Psalmotoxin

Product Description

Psalmotoxin 1,Catalog Number: O1120-V,Lyophilized,Purity≥95%

 

ASIC1a channels, Psalmotoxin-1 inhibits cation currents mediated by acid-sensing ion channels (ASIC1a).

Psalmotoxin (PcTx1) is a spider toxin from the venom of the Trinidad tarantula Psalmopoeus cambridgei. It selectively blocks Acid Sensing Ion Channel 1-a (ASIC1a), which is a proton-gated sodium channel.

Sources


Psalmotoxin is a toxin produced in the venom glands of the South American tarantula Psalmopoeus cambridgei.

Chemistry


The psalmotoxin structure can be classified as an inhibitor cystine knot (ICK) protein. Many ion channel effectors from snail, spider, and scorpion venoms share a similar ICK structure, although they possess very different pharmalogical profiles. Among ICK toxins, psalmotoxin is the only peptide known to act on homomeric ASIC1 channels.

Psalmotoxin is a 40-amino acid peptide, possessing 6 cysteines linked by three disulfide bridges. The three-dimensional structure consists of a compact disulfide-bonded core from which three loops and the N and C termini emerge. The main element of the structure is a three-stranded antiparallel β-sheet.