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H4-K20ac Catalog Number H4204 Lyophilized Store At -20°C Or -80°C
Chemically synthesized histone H4 protein, corresponding to residues within 1-102 of human histone H4, acetylation at K20.
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. H4K20ac is associated with gene repression in human cells. Unlike H3K9me3, a constitutive heterochromatin mark, H4K20ac was less associated with TSSs of completely silenced genes (those with no mRNA expression), suggesting that H4K20ac may play a role in repressing transcribed genes rather than in assisting with heterochromatin formation to induce a fully silent state, possibly preventing methylation on the same residue.
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H4-K20ac Catalog Number H4204 Lyophilized Store At -20°C Or -80°C
Chemically synthesized histone H4 protein, corresponding to residues within 1-102 of human histone H4, acetylation at K20.
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. H4K20ac is associated with gene repression in human cells. Unlike H3K9me3, a constitutive heterochromatin mark, H4K20ac was less associated with TSSs of completely silenced genes (those with no mRNA expression), suggesting that H4K20ac may play a role in repressing transcribed genes rather than in assisting with heterochromatin formation to induce a fully silent state, possibly preventing methylation on the same residue.